Top 20 Cities in the U.S. for Weekend Getaways

Weekends are a great opportunity to break free from the routine and go on an adventure, and the United States offers many exciting destinations for unforgettable weekend getaways.

No matter if you crave the action of big cities, the serenity of natural beauty, or a blend of both, I have 20 of the best U.S. cities that you can go to for a weekend getaway. 

Each of the destinations offers a unique combination of relaxation and excitement, perfect for your next weekend escape. 

1. New York City, New York

New York City is the city that never sleeps and because of that is a great place to have a weekend escape. Marvel at iconic landmarks like Times Square, Central Park and the Statue of Liberty. 

You can catch a Broadway show, explore historic neighborhoods like Greenwich Village, and enjoy diverse culinary experiences. The city’s vibrant energy, cultural richness, and world class attractions make it an unbeatable destination for a memorable weekend getaway. 

The city also offers an extensive public transportation system which makes it easy to navigate and maximize your weekend experience. 

If your looking for Instagrammable spots in New York City, click the link to check out Sarah’s post on “Lust ‘Till Dawn”, featuring 23 amazing photo locations across the city.

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2. San Francisco, California

San Francisco is situated along the stunning Bay Area, promises a weekend filled with breathtaking vistas and cultural delights. You can see the iconic Golden Gate Bridge, visit Alcatraz Island, and take a ride on a historic cable car. 

Have some clam chowder down at the Fisherman’s Wharf. Don’t forget your jacket. You’ll thank me later. There are also numerous neighborhoods to visit that all have their own special character. 

San Francisco has a blend of natural beauty and urban charm which makes it a perfect choice for a weekend getaway. 

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3. Charleston, South Carolina

Charleston is steeped in Southern hospitality and historical charm, and is an ideal weekend destination. Wander along the cobblestone streets adorned with antebellum architecture and explore historic plantations such as Boone Hall.

You can shop on King Street and the Charleston City Market, enjoy Lowcountry cuisine, take a horse drawn carriage ride through downtown, take a stroll down the Battery and take a cruise on the harbor. 

The city has a warm ambiance and rich history. Charleston provides a delightful weekend experience. 

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4. Chicago, Illinois

Chicago, known as the Windy City, beckons with its unique blend of architectural wonders and culinary delights. You can marvel at the iconic skyline with the Willis Tower and the historic Wrigley Building. 

Enjoy the city’s culinary scene with a mouthwatering deep dish pizza experience, and explore cultural institutions like the Art Institute of Chicago. Take an architectural boat tour to gain perspective on the city’s impressive buildings.

The city’s vibrant art and music scene, many different sports teams, along with its friendly atmosphere, ensure a weekend to remember. 

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5. New Orleans, Louisiana

New Orleans, the vibrant heart of Louisiana, promises a weekend filled with lively music, rich history, and culinary indulgence. Soak up the French Quarter, where jazz fills the air, and you can savor iconic beignets at Cafe du Monde. 

You can explore historic sites like St. Louis Cathedral and the lively atmosphere of Bourbon Street. You can take a leisurely steamboat cruise along the Mississippi River.

New Orleans offers a unique blend of culture and entertainment for a memorable weekend escape. 

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6. Miami, Florida

Miami beckons with its sun soaked beaches, pulsating nightlife, and cultural diversity. You can spend your weekend on South Beach, where the iconic Art Deco architecture adds character. 

Soak up the thriving Latin culture of Little Havana, sipping Cuban coffee and savoring flavorful cuisine. Miami’s vibrant art scene is showcased in Wynwood Walls. You can also take a scenic helicopter tour to capture the city skyline and beautiful coastline. 

All of these factors and more make Miami a wonderful place to escape for a weekend. 

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7. Seattle, Washington

Seattle, is surrounded by stunning natural beauty, and invites you for a weekend filled with urban charm and outdoor adventures. You can explore Pike Place Market, where you can buy fresh seafood and see local artisans.

Ascend the Space Needle for a wonderful panoramic view of the city and the Puget Sound. To get a different perspective of the city, you can kayak or paddleboard on Lake Union.

You can also take a ferry ride to Bainbridge Island. or you can explore Olympic National Park or Mount Rainier National Park to hike and enjoy the natural wonders of the Northwest. 

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8. Austin, Texas

Austin, the “Live Music Capital of the World,” offers a dynamic weekend filled with live music, diverse culinary experiences and outdoor activities. You can take in the sounds of Sixth Street’s bars and venues.

If you want to get out to enjoy the outdoors and get some exercise, you can go to Lady Bird Lake to take a walk, paddleboard, or kayak. You can also rent a bike and explore the scenic Barton Creek Greenbelt.

Austin is known for its barbeque and a couple great spots to indulge yourself is Franklin Barbecue and Micklethwait Craft Meats. 

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9. Las Vegas, Nevada

Las Vegas is the ultimate entertainment destination and guarantees an exciting weekend getaway. You can explore the Las Vegas Strip with its world famous casinos, catch unforgettable live shows, and dine at celebrity chef restaurants. 

If you would like a change of pace, consider hiking in Red Rock Canyon or take a day trip to the engineering marvel the Hoover Dam. 

The city offers a thrilling blend of entertainment and natural beauty. Don’t forget, what happens in Vegas stays in Vegas. 

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10. Nashville, Tennessee

Nashville is fondly known as “Music City”. It welcomes you with its rich musical heritage, delicious Southern cuisine, and friendly atmosphere. 

You can explore the Country Music Hall of Fame, take a tour of the Ryman Theater, enjoy live shows along Broadway, see art exhibits at Frist Art Museum, and savor hot chicken at Hattie B’s. Hattie B’s is where I had the best chicken sandwich I have ever had.

Don’t miss the opportunity to tour the historic RCA Studio B, where music legends recorded their hits. Plus, take a backstage tour of the iconic Grand Ole Opry.

If you are interested in a travel itinerary for Nashville, you can read my blog post titled “3 Day Travel Itinerary for Nashville, TN”

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11. San Diego, California

San Diego is a coastal paradise with its Mediterranean climate. It’s a perfect weekend getaway destination with its beautiful beaches and family friendly attractions. 

Explore Balboa Park, home to the San Diego Zoo and numerous museums. La Jolla Cove offers water sports and wildlife encounters. You can enjoy seafood at waterside restaurants in Seaport Village. 

With its scenic beauty and relaxed atmosphere, San Diego promises a weekend to rejuvenate you for the week ahead. 

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12. Denver, Colorado

Denver is known as the “Mile High City”. The city is the gateway to the Rocky Mountains and it offers an ideal weekend retreat for people who enjoy the outdoors. 

Explore the River North Art District (RiNo), known for its vibrant arts scene, and visit the Denver Art Museum.

If the outdoors is your thing, you can hike in nearby Rocky Mountain National Park or hit the slopes for skiing and snowboarding in the winter. You can also take in a concert in the outdoor Red Rocks Amphitheater. 

No matter what you do, Denver’s blend of cultural attractions and natural beauty ensures an enriching weekend getaway. 

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13. Portland, Oregon

Portland is a hot spot for foodies, nature lovers, and creatives. In Portland, you can spend your weekend sampling a diverse array of cuisines from the city’s famous food carts, and get lost in the stacks at Powell’s City of Books.

You can explore the tranquil Lan Su Chinese Garden and soak in the stunning Multnomah Falls, hike the trails in Forest Park or rent a bike to explore the city’s many bike friendly neighborhoods and scenic routes.

Portland’s relaxed vibe and lush surroundings create a perfect weekend escape.

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14. Boston, Massachusetts

Boston is one of America’s oldest cities and it offers a weekend steeped in history, culture, and charm. 

You can walk the Freedom Trail to discover popular sites like Independence Hall and Faneuil Hall. Explore world class museums such as the Museum of Fine Arts and the Isabella Stewart Gardner Museum. 

To enhance your historical experience, take a guided tour of the USS Constitution, the oldest commissioned warship afloat in the world. 

Plus, don’t forget to try the delicious clam chowder at the Quincy Market, or take a scenic stroll along the Charles River Esplanade. 

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15. San Antonio, Texas

San Antonio’s rich history and vibrant culture make it an inviting weekend destination. You can explore the historic Alamo and the San Antonio Missions, a UNESCO World Heritage Site. 

Stroll along the picturesque San Antonio Riverwalk, where you can dine at charming waterside restaurants, enjoy boat tours or do some shopping. Take a scenic riverboat cruise to learn about the city’s history while enjoying the scenic views.

The city’s blend of historical significance and modern charm ensures an enriching and relaxing weekend.

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16. Philadelphia, Pennsylvania

Philadelphia, is known as the “City of Brotherly Love,” except when they are booing Santa, is a history lover’s paradise.

You can spend your weekend exploring Independence Hall, viewing the Liberty Bell, and discovering the fascinating National Constitution Center.

If art is more your thing, you can take a self guided tour of the city’s vibrant mural arts scene for a unique cultural experience.

Plus, don’t forget to try a classic Philly cheesesteak sandwich from renowned spots like Pat’s King of Steaks and Geno’s Steaks. 

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17. Honolulu, Hawaii

Honolulu is located on the beautiful island of Oahu. It offers a tropical weekend escape with its stunning beaches, warm weather, and cultural attractions.

You can relax on the world famous Waikiki Beach, surf legendary waves on the North Shore, hike to the top of Diamond Head, and view history at the USS Arizona Memorial at Pearl Harbor. 

The city has a vibrant culture that can be seen at hula performances and traditional luaus, making it a perfect destination for a weekend filled with relaxation and exploration. 

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18. Phoenix, Arizona

Phoenix, is the capital of Arizona and it invites visitors with its desert landscapes, outdoor adventures, and cultural offerings.

Spend your weekend exploring the Desert Botanical Garden, taking a hike in Camelback Mountain, floating in a hot air balloon over the Sonoran Desert and learning about Native American history at the Heard Museum.

You can savor delicious Southwestern cuisine at local restaurants, and enjoy the city’s warm weather, making it an ideal getaway for nature enthusiasts and culture seekers alike. 

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19. Savannah, Georgia

Savannah is a city that is steeped in Southern charm. The city is a picturesque weekend destination with its historic squares, Spanish moss draped trees and antebellum architecture. 

In Savannah, you can take a leisurely stroll through Forsyth Park, visit the Mercer Williams House, explore the historic district on a horse drawn carriage ride, and take a haunted history tour if you dare. 

Savor classic Southern cuisine at renowned restaurants like The Grey and Leopold’s Ice Cream. Savannah’s unique blend of history and hospitality promises a delightful weekend escape. 

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20. Santa Fe, New Mexico

Santa Fe, is the oldest capital city in the United States. It boasts a distinctive blend of Native American, Spanish, and Anglo cultures. 

You can spend your weekend exploring the historic Plaza, home to art galleries, shops and the Palaces of the Governors. 

Visit the stunning Loretto Chapel with its miraculous staircase and indulge in the city’s renowned Southwestern cuisine. Make sure to explore the nearby Bandelier National Monument for a glimpse into the region’s ancient history and stunning landscapes.

Santa Fe’s rich cultural heritage and artistic vibrancy create an enchanting weekend getaway filled with exploration and relaxation. 

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Final Thoughts

These 20 U.S. cities offer an array of experiences, from cultural immersion to outdoor adventures, making them perfect weekend getaway destinations. 

Whether you seek the bright lights of the big city or the tranquility of coastal shores, there’s a city on this list to suit your preferences. 

So, pack your bags, plan your itinerary, and embark on a weekend adventure to one of these incredible destinations for an unforgettable experience.

If you are interested in learning more about travel destinations, saving on travel, and credit card points and miles visit my blog Travelwidstom.